What is Herpes Simplex Virus?

Herpes Simplex Virus (HSV-1, HSV-2) is an infectious disease and is widespread among both men and women.

Frequent infections of the disease occur due to the internal reactivation of the virus. There are several factors that increase the risk of reinfection, such as:

Exposure to sun, fever, local injury, neglecting the trigeminal nerve, menstrual cycle, and emotional stress.

HSV-1 and HSV-2 differ serologically. HSV-1 mainly transmits through direct contact with oral fluids. And it is usually linked with oral inflammations and lesions above waist level. Meanwhile, HSV-2 primarily transmits through genital secretions. And it is linked to inflammations and genital lesions under waist level. Nevertheless, the relation between the type of the virus and the location is not definitive.

One can contract the virus directly from the symptomatic excretors, or asymptomatic excretors.

Herpes Simplex Virus causes acute and deadly inflammations for newborns and people with immunodeficiency. Pregnant women with HSV have twice and triple the risk of getting a miscarriage. Fluids of active herpes in the genital secretions of pregnant women may infect the newborn and risk their life if not treated properly.

Pros of Laboratory Tests

Tests can discover the Herpes Virus, especially IgM, one week after the contraction. IgM usually indicates the presence of active or recurrent infection.

IgG mostly shows two or three weeks after the initial contraction. But might disappear from the titer test after a few months.

Herpes IgG seroconversion from negative to positive also indicates an active or recent and recurrent infection.

Some people who suffer from recurrent infections of the virus may not have an abnormal rise in the calibration test. Discovering IgG helps evaluate the immunological state of the patient, and is a serological indicator of previous infections of HSV.

Experts recommend taking a matched antibody pairs test to reveal the seroconversion in order to diagnose the recent infection of Herpes Simplex Virus (first time or recurrent) accurately.

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