Dopamine Agonists Link with Parkinson’s Disease – FinD The Full Answer Here

Dopamine agonists are chemicals or medications that imitate and replace dopamine when the dopamine levels are low. This hormone, dopamine, has a critical role in the body, and having sufficient levels of this hormone contributes to maintaining the health and functions of the brain, mood, and even the digestive system.

Dopamine Agonists Facts

  • They contribute to improving PD symptoms, especially in early stages and for patients less than 60 years old.
  • Dopamine agonists have less movement-related side effects compared to levodopa, which is used to relieve PD.
  • Fluctuations or changes in the dopamine levels in the body contribute to having serious symptoms or diseases, including different mental diseases.
  • Can cause dizziness, fainting, or sudden sleepiness, which can be dangerous when performing tasks that require alertness, like driving.
  • Similar to other medications that compensate for the loss of a certain agent -here dopamine- they might cause withdrawal syndrome, which includes symptoms such as sudden severe fever, muscle spasms, kidney failure, sleep disorders, mood swings, and aches.

How Do Dopamine Agonists Work?

Dopamine Agonists are prescribed in case of movement-related or hormone-related disorders. These medications help relieve sleep disorders, pain, and emotional disorders related to dopamine deficiency. They are not, however, as effective as levodopa, which is a medication for relieving PD, but their movement-related side effects are much less. Dopamine agonists are even helpful for the early treatment of Parkinson’s disease.

Side Effects of Dopamine Agonists

The side effects of dopamine agonists might differ depending on the medication (ergoline or non-ergoline), dose, and how long has the medication been used. In case of having any side effects, one should not only stop taking the medication, but must immediately inform the doctor. The side effects might be mild and disappear in a few days, or severe that one has to stop taking the medication.

In general, the side effects of dopamine agonists include the following:

  • Headache.
  • Dry mouth.
  • Heart valve problems and heart failure.
  • Nausea, vomiting, heartburn, and constipation.
  • Runny nose.
  • Memory or focus problems.
  • Hypertension, and hyoptension.
  • Dyskinesia.
  • Sudden sleepiness, dizziness, or fainting.
  • Increased heartbeat rate.
  • Megalomania.
  • Swelling in the legs or arms.

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